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Why Retatrutide Side Effects May Differ The glucagon receptor component adds unique considerations: Increased Thermogenesis Glucagon activation increases energy expenditure, which may cause slight increases in heart rate or body temperature in some patients

By modifying the peptide structure, pharmaceutical companies extended the half-life to days or weeks, allowing once-weekly injections to maintain therapeutic levels

Possible Side Effects Injection site pain or redness Mild and temporary

Inositol (50 mg/mL): Helps metabolize fats and cholesterol

Effective options include oral GLP-1s like the Wegovy pill and Foundayo, as well as orlistat, Qsymia, Contrave, and phentermine