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Results of the study showed an 84% event-free survival rate after four years compared with 73% in an external control arm

Consequently, the transformation of LC3-I to the autophagosome-associated form LC3-II is weakened, thereby reducing Beclin-1 and autophagy-related gene 5 expression and decreasing autophagy vesicle formation [129]

However, the mechanisms behind these changes are largely unknown and may be related to the regulation of the nervous system by inulin metabolites