27 The second tool was the Frailty Index (FI) accumulation of deficit (40 items), which is the short form of the original 70-item FI accumulation of deficits
This is why your maintenance calories may be lower than a calculator suggests for someone your size who was never overweight
Polena H, Boudou F, Tilleul S, Dubois-Colas N, Lecointe C, Rakotosamimanana N, Pelizzola M, Andriamandimby SF, Raharimanga V, Charles P, et al
12 The substitution of GLP-1 Thr 13 or GIP Ile 7 with Ala obviously decreased their receptor-activating activities 25,26 and the substitution of GIP Ile 7 with Thr decreased its cAMP activity (pEC 50 : 9.769.58;Emax: 9.918.90)
Gastrointestinal side effects may be serious enough to force patients to stop treatment, thus limiting the effectiveness of these medications [7]