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A549 and H358 KRAS mutant lung cancer cells examined in vitro were treated with potent senescence inducers, such as aurora kinase inhibitors: Alisertib and Barasertib [135]

However, some safety concerns have been raised in patients with serious health conditions

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However, prolonged failure to reestablish normal mitochondrial metabolism may promote the progression of AKI to chronic kidney disease (CKD) (Shen et al., 2020)