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Parasitology (2018) 145:4259

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These results show CHO R C5/Bcl-2 cells to be less sensitive to tamoxifen collateral sensitivity than CHO R C5 cells (IC 50 0.593 0.28 M versus 1.49 0.23 M, respectively), consistent with a protective effect likely due to the overexpression of recombinant huBcl-2