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Fasting glucose should normalize or approach normal ranges within 8 to 12 weeks

doi: 10.1128/MCB.19.5.3278 21 PucheJECastilla-CortzarI

GLP-1 is likely best described as a neuropeptide with physiologically and pharmacologically relevant effects on food intake and body weight (116, 117), potential neuromodulatory roles, and possible effects in a range of other neuropathological conditions including neurodegenerative diseases (e.g., Alzheimer's, Parkinson's), brain trauma and stroke, as well as in depression, anxiety and addiction (118123)

It achieves this through several mechanisms: Activation of GLP-1 Receptors : When semaglutide is injected, it binds to and activates GLP-1 receptors in the brain, particularly in areas that regulate appetite and food intake

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