Clinically Relevant Experimental Animal Models Because of the limitations/difficulties related to human studies due to in part to ethical concerns, the use of experimental animal models becomes an important alternative to investigate disease pathogenesis
provided evidence of B cell ferroptosis in SLE patients and SLE mouse models, suggesting that ferroptosis may regulate B cell differentiation and plasma cell formation, thereby implicating this process in SLE pathogenesis [102]
Herbal nanoformulation design considerations encompass other factors such as cost-effectiveness, ease of fabrication, and scalability in manufacturing processes
Antioxidant vitamins are present on the cell membrane, intracellularly, or extracellularly, and react with free radicals to either remove or inhibit them
NAC is not necessarily better than glutathione for detoxification, but it works differently