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M.ZawadaA.DobrowolskaA.Krela-KamierczakI

Understanding the genetic basis of GLP1 medication treatment response is of substantial clinical importance

Researchers started working with peptides in the 1920s, and synthetic peptides have been used to treat diabetes ever since

539 Results from several Phase III clinical trials (ORION-9/10/11, NCT03397121, NCT03399370, and NCT03400800) have shown that subcutaneous injections of inclisiran every 6 months considerably reduce LDL-C levels by 4852%, demonstrating sustained efficacy and good tolerability

Although promotion of angiogenesis and cell proliferation could entail benefits in the short-term in terms of tissue healing, this could be a double-edged sword, as these same processes are how many cancers initiate and spread