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[2] [4] In multi-compartment pharmacokinetics, two operational half-lives are often distinguished: an early distribution () half-life governed by redistribution from the central to peripheral compartments, and a later elimination () half-life governed by metabolic clearance and excretion

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Cell culture and T cell preparation Human breast cancer cell lines SKOV3 (ATCC HTB-77), BT474 (ATCC HTB- 20), MDA-MB-231 (ATCC HTB-26), and MDA-MB-468-CD33 30 were cultured in Dulbeccos Modified Eagle Medium (DMEM) (Corning) with 10% (v/v) fetal bovine serum (FBS) (Gibco)