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doi: 10.3389/fimmu.2025.1719005 Received 05 October 2025 Revised 04 December 2025 Accepted 15 December 2025 Published 08 January 2026 Volume 16 - 2025 Edited by Shue Wang, University of New Haven, United States Reviewed by Abhishesh Kumar Mehata, University of California, Davis, United States Kyung-Ho Roh, University of Alabama in Huntsville, United States Nadia Barbero, University of Turin, Italy Updates Copyright 2026 Zou, Chen, Chen, Wang and Zheng