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The lyophilisate is dissolved with bacteriostatic water introduced on the inside wall of the vial, without a violent jet onto the powder and without vigorous shaking see Reconstitution Protocol section above for detailed procedure

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For example, it has been found that polydatin promotes mitochondrial biogenesis and protects against mitochondrial oxidative stress via the activation of Sirtuin-1-PGC-1 pathway and Sirtuin-1-Nrf2-ARE pathway in kidney diseases (Huang et al., 2015