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To complement experimental insights, machine learning models were employed to predict rivaroxaban solubility based on temperature, solvent type, and mass fraction of dichloromethane

On an annual basis, the Fund's Institutional Class delivered a total return of 16.00% in 2025, compared to 17.37% for the Russell 1000, reflecting the impact of sector allocation and company-level developments such as gains in pharmaceutical and payment processing holdings and weakness in certain Consumer Staples names

van Dooren FE, Nefs G, Schram MT, Verhey FR, Denollet J, Pouwer F

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consulted for Eli Lilly & Co., and D.H.vR