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Recently, additional biomarkers, such as B7-H4 (associated with poor prognosis), circulating cell-free DNA (cfDNA), and mutation-specific circulating cell-free tumor DNA (cftDNA), have been identified as potential indicators of tumor burden and volume [131,132,133]

For up to two years, 199 premenopausal women received part in the study

Each technique reveals complementary data, contributing to a holistic understanding of GHK-Cu