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qPCR analysis confirmed that Rf regulates critical genes, including ANXA2, BAZ1A, DNMT3L, and MMP9, thereby clarifying its underlying mechanism of action

Regulatory agencies increasingly recognize the value of surrogate endpoints, adaptive trial designs, and biomarker-driven patient stratification, particularly in areas of high unmet need

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If you experience persistent pain, significant swelling, or signs of infection such as warmth, pus, or fever, contact your healthcare provider promptly