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Youll find their exact statements in quotation marks below, though the remaining part of their reviews was slightly paraphrased for clarity

Based on large-scale real-world data from late 2025, super responders are generally defined by: The 15% Threshold: Losing more than 15% to 20% of their total body weight within the first year of treatment. Immediate Satiety: An almost instantaneous "silencing" of cravings and "food noise," often occurring within hours of the very first starter dose

Psychiatry 76 , 970976 (2014)

doi: 10.1186/s12951-024-02808-7 204 LiHYuKHuHZhangXZengSLiJet al