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Although treatment of persons with cyroglobulinemia-related glomerulonephritis has led to improvement in the renal disease as defined by decreased levels of cryoglobulin, rheumatoid factor and creatinine134, 135, relapse is common, even with the use of combination therapy136, 137

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37 Furthermore, the Corporate Practice of Medicine (CPOM) doctrine in states like California and New York prohibits corporations from practicing medicine