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Cascella R, Evangelisti E, Zampagni M, Becatti M, DAdamio G, Goti A, Liguri G, Fiorillo C, Cecchi C

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At age 40, the loss is approximately 30%, and increases to as much as 50% reduction by age 65

Addition of 100 mM ethanol to a human neuronal cell model, SH-SY5Y cells, showed the secreted amount of BDNF and the cyclic AMP-responsive element-binding protein (CREB) activity to be significantly reduced by ethanol

ProQuest, 12(18), p.5915