is semaglutide a glp-1 Another Weight-Loss Trial Win for Weekly Drug What Is GLP-1 and Why

Design: Single center (Mayo Clinic) from 2014 and 2022, with 16-week follow-up (last date of follow-up, May 9, 2022)

Varas Lorenzo MJ, Lopez Martinez A, Gordillo Bernal J, et al

(2016) 11:e0163747

a) Alpha cells b) Beta cells c) L-cells d) K-cells Answer: c) L-cells GLP-1 secretion is stimulated by: a) Fasting b) Stress c) Food intake d) Exercise Answer: c) Food intake One major function of GLP-1 is to: a) Increase glucagon b) Inhibit insulin c) Stimulate glucose-dependent insulin release d) Stimulate lipolysis Answer: c) Stimulate glucose-dependent insulin release GLP-1 slows: a) Hepatic metabolism b) Gastric emptying c) Renal excretion d) CNS transmission Answer: b) Gastric emptying The enzyme that rapidly degrades GLP-1 is: a) MAO-B b) COMT c) DPP-4 d) PKA Answer: c) DPP-4 Which of the following is a central effect of GLP-1

This selectivity is crucial for understanding the therapeutic effects and potential limitations of single-receptor activation compared to Retatrutides multi-receptor approach