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Based on ASM's data submission requirements discussed in section III.C.2.d.(1) of this final rule, we believe that this data reporting and scoring structure does not create an issue with attributing relevant measures and performance to ASM participants in the cohort

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Intramuscular Injections Subcutaneous Injections Additional information Additional information Key Benefits of Each Compound Tirzepatide + L-Carnitine Supports appetite regulation & satiety Helps reduce cravings & food noise Supports metabolic wellness & body composition AOD-9604 Supports fat metabolism pathways Commonly utilized for body recomposition support Helps support lean muscle preservation during calorie deficits MOTS-C Supports mitochondrial energy production Helps improve metabolic efficiency & endurance Commonly utilized in cellular performance & longevity protocols Tesamorelin Supports visceral fat optimization Helps support recovery & growth hormone signaling Commonly utilized in advanced physique & metabolic protocols Why They Work Well Together This protocol combines: appetite & metabolic regulation fat metabolism support mitochondrial energy optimization recovery & body composition support Rather than focusing only on weight loss, the goal is creating a more complete metabolic optimization protocol that supports energy, recovery, performance, and healthier long-term body composition

The clinicians selected as ASM participants starting the 2027 ASM performance year/2029 ASM payment year is made public in a form and manner determined by CMS

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