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Drug development from the bench to the pharmacy: with special reference to dipeptidyl peptidase-4 inhibitor development
Journal of Cell Science
While density for the N-terminal lipidation was not visible in the lower resolution cryo-EM map of the repeat Cagri-CTR-Gs complex ( N = 2), the outward rotamer of H296 ECL2 was observed, congruent with similar interactions between the N-terminal acylation and ECL2
doi: 10.2337/cd22-0027
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