TAS2R5 has been identified in L cells that secrete GLP-1, TAS2R38 is expressed in enteroendocrine cells (EECs) and has been related to CCK, PYY, and GLP-1 secretion (71, 72)
(59), peripheral administration of PP attenuates food intake and gastric emptying, while icv injection of PP increases food intake and delays gastric emptying, but it is not excluded that PP effects on food intake are secondary to changes of gastric emptying (59)
Segn las guas actuales de la American Diabetes Association (ADA), estos medicamentos pueden considerarse como terapia inicial o adicional en pacientes con diabetes tipo 2, especialmente aquellos con enfermedad cardiovascular establecida, alto riesgo cardiovascular, enfermedad renal crnica o insuficiencia cardaca, independientemente del uso de metformina
GLP-1 Receptor Agonists and Reduction of Cardiometabolic Risk: Potential Underlying Mechanisms
National Diabetes Audit 2010-2011 Report 2: Complications and Mortality