surpass-2 tirzepatide vs semaglutide weight loss Efficacy of versus in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the Trial | Diabetologia Tirzepatide vs Semaglutide for Weight

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New data published in JCI insight suggests that co-administration of semaglutide and a -hydroxybutyrategenerating ketone ester for three weeks prevented semaglutide-induced changes in gene expression related to mitochondria and muscle atrophy

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About SURMOUNT-5 SURMOUNT-5 (NCT05822830) was a 72-week, multi-center, randomized, open-label, Phase 3b trial evaluating the efficacy and safety of Zepbound (tirzepatide) compared with Wegovy (semaglutide) in adults with obesity, or overweight with at least one of the following comorbidities: hypertension, dyslipidemia, obstructive sleep apnea (OSA) or cardiovascular disease, who did not have diabetes

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