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Kuroki T, Tanaka R, Shimada Y, Yamashiro K, Ueno Y, Shimura H, et al

According to Mahmoud Salama Ahmed, a medical chemist at Texas Tech, up to 40% of the weight you lose on a GLP-1 is lean muscle

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In June 2025, MBX Biosciences In announced it received preliminary feedback from the FDA on its planned Type B pre-IND meeting, supporting the advancement of its EL-22 program in combination with GLP-1 receptor agonists toward a Phase 2 clinical trial