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Repeated freeze-thaw cycles should be avoided when possible, as each cycle can cause incremental loss of activity through partial aggregation

Materials and methods: Mouse macrophage J744A.1 cells were treated with uric acid at increasing concentrations of 200 to 800M

Supplementary material The Supplementary Material for this article can be found online at: References 1 AdamsJ

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The significance of this new study cannot be overstated - while we've known that paraxanthine can provide similar benefits to caffeine with potentially fewer side effects, this research suggests it may actually be superior for cognitive enhancement and brain health