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Oral administration to diet-induced-obese mice for ~10 days reduces fat mass without altering food intake, decreases adipocyte size, restores insulin sensitivity, and increases adipose NAD and SAM levels [2]

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Available at Last updated 02/06/2018

The 12mg dose produced average weight loss of approximately 71.2 lbs (32.3 kg) over 68 weeks, with retatrutide 9mg reducing WOMAC knee pain scores by up to 75.8%