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If successful, semaglutide would be just the second drug the FDA has approved for treatment of MASH
Medicated weight loss options include: Mounjaro - a weekly self-administered injection that suppresses your appetite Orlistat (sometimes known by the branded version Xenical) a daily pill Saxenda a daily self-administered injection Wegovy a weekly self-administered injection - this is not available in the UK yet To use a weight loss treatment a pharmacist or clinician will need to check if theyre suitable for you
As weight, blood sugar, and insulin regulation improve, other areas like kidney function, fertility, and cardiovascular risk often improve alongside them
Metabolic Optimization Both compounds improve metabolic function through different pathways
Assessment may include body composition measurement (DEXA scan, bioelectrical impedance), serum muscle markers, and review of protein intake and exercise adherence to identify modifiable gaps
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