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It has also been reported that in response to increased -cell death in induced murine models of diabetes (STZ alone or in combination with a high fat diet) and in a genetic mouse model of T2D, islet macrophages exhibited increased expression levels of insulin like growth factor 1 (IGF-1), concomitant with decreased expression of IL-6 and TNF, a profile that is associated with a reparative phenotype (77)

Gunes, S., Al-Sadaan, M

23 months), human fecal metabolite studies ( n = 6 omnivores and n = 7 vegans/vegetarians) in the conversion of d 9 -l-carn to d 9 -TMA ( A ), d 9 -l-carn to BB ( B ), or d 9 -BB to d 9 -TMA ( C )

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Am J Physiol Gastrointest Liver Physiol 294:G208-216