ROS dysregulation in metabolic diseases ROS play a pivotal role in the etiology of metabolic diseases such as diabetes and obesity [25]
Patient-centered approach: Provide individualized education and support to encourage adherence to lifestyle changes and self-care behaviors
No difference was seen in the source of serum (SMD = 1.24, 95% CI: 2.79 to 0.31, and p = 0.117), plasma (SMD = 0.05, 95% CI: 1.43 to 1.34, and p = 0.948), erythrocyte (SMD = 0.97, 95% CI: 1.94 to 0.00, and p = 0.050), or blister fluid (SMD = 0.29, 95% CI: 1.56 to 0.98, and p = 0.657) (Figure 3(a))
More than 300 proteins were significantly altered between the control and ibuprofen-treated groups
Results are usually subtle and temporary, making topical formulations more suitable for daily skincare maintenance rather than treating stubborn pigmentation or uneven tone