Because I think that beyond the studies that we have showing that there are certain subsets of people who are GLP-1 deficient, like I mentioned, I think that some folks are actually GLP-1 deficient perhaps genetically or struggling with it for various different reasons
The main incretin hormones secreted by the epithelial cells of the gastrointestinal track are glucagon-like peptide-1 (GLP)-1 and glucose-dependent insulinotropic peptide, also known as Gastric Inhibitory Polypeptide (GIP), which stimulate the pancreatic cells ( and cells) and regulate insulin secretion with respect to blood glucose concentration ( The first incretin to be reported was GIP
Link Subhan, Z., & Hindmarch, I
It is not surprising that robust weight loss, reduction in liver and abdominal fat [30] and improvement in insulin sensitivity [31] associated with tirzepatide treatment may likely affect this key pathophysiological state associated with elevated BP in this population
We know that every patient is unique, and therefore each treatment plan is highly customizable