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MT-2 is the correct choice when the research objective is to study the broader melanocortin network, or when the interaction of multiple receptor subtypes is itself the variable of interest

[PubMed: 17148552] 620

PPAR- agonists are shown to reduce atherosclerotic lesions and hepatic fat accumulation in the ApoE / FXR / mouse model by promoting -oxidation of fatty acids and increasing liver to absorb fatty acids from plasma