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KLOW binds to klotho receptors expressed in kidney, liver, adipose tissue, and vascular endothelium
Similarly, in RBCs from chronic lead-exposed rats, oxidative stress and K + loss were found to accelerate Fas translocation into lipid raft microdomains, inducing Fas-mediated death signaling [169]
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During Salmonella Typhimurium infection, C16-carnitine localizes to regions of immune cell destruction, and C16-carnitine acts as a local immunoregulatory molecule that significantly interferes with host immune homeostasis by affecting the number and function of specific immune cell populations, such as T cells and B cells, suggesting that the accumulation of LCACs is part of the pathogen immune evasion strategy [60]
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