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In WT mice, both AOD9604 and hGH elevated plasma glycerol levels, indicating enhanced lipolytic activity

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In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

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Low blood levels of vitamin B12 have been linked with a number of major health conditions, including dementia, depression, osteoporosis and age-related macular degeneration