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625 - 638 Copyright The Authors 2019 Carnitine is a vitamin-like substance that plays a vital role in the -oxidation of long-chain fatty acids (FA) to produce energy by transporting them from the cytosol to the mitochondrial matrix, via carnitine palmitoyltransferase 1 (CPT1) ( Reference Bremer 1 , Reference Zammit, Ramsay and Bonomini 2 )

It was originally created in the 1990s to treat rare genetic diseases and skin conditions but, as with many medications, has grown in popularity for its myriad of off-label uses

Bergenstal et al

Should patients with a history of gallbladder cancer or other gallbladder disorders take GLP1-RAs

Ning Y, Shang Y, Huang H, Zhang J, Dong Y, Xu W, Li Q