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Pancreatic -cell electrical activity and insulin secretion: of mice and men

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115 In addition, liver insulin also effectively regulates lipid metabolism primarily by promoting cleavage and nuclear translocation of the sterol regulatory element binding protein 1c (SREBP-1c) 116,117 that activates lipogenesis in hepatocytes

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In some cases, weight loss may also cause a drop in blood pressure, leading to circulation problems