Major Criteria Congenital multiple contractures, characteristically adduction-flexion contractures and/or talipes equinovarus (clubfoot) Characteristic craniofacial features, which are evident at birth or in early infancy Characteristic cutaneous features including skin hyperextensibility, easy bruisability, skin fragility with atrophic scars, increased palmar wrinkling Minor Criteria Recurrent/chronic dislocations Pectus deformities (flat, excavated) Spinal deformities (scoliosis, kyphoscoliosis) Peculiar fingers (tapering, slender, cylindrical) Progressive talipes deformities (valgus, planus, cavum) Large subcutaneous hematomas Chronic constipation Colonic diverticula Pneumothorax/ pneumohemothorax Nephrolithiasis/cystolithiasis Hydronephrosis Cryptorchidism in males Strabismus Refractive errors (myopia, astigmatism) Glaucoma/elevated intraocular pressure Myopathic EDS (mEDS) If a person meets the diagnostic criteria for mEDS, genetic testing should be done to confirm the diagnosis
Some researchers in the Canadian peptide space stack MOTS-C with Retatrutide for metabolic optimization rather than direct fat loss
Nuwhite S-Acetyl Glutathione With Collagen A strong contender in the Philippine market, Nuwhite combines 250mg of S-acetyl glutathione (a more stable form) with skin-nourishing collagen and vitamins C and E
BPC 157 stimulated both egr-1 and its co-repressor gene nab2 (Tkalcevic et al., 2007)
