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These are pragmatic, opinion-based observations rather than evidence-based recommendations, and neither approach has been shown to be clinically superior

One Mayo Clinic forum discussion acknowledged that an alternating 6-month approach is "creative" and might allow you to get benefits from both while minimizing cumulative side effects

The study from Zheng et al

For example, Mounjaro (tirzepatide)by Eli Lilly, though structurally a dual GIP/GLP-1 agonist, is classified within the GLP-1 class in major market reports, and reached $5.16 billion in sales in its first full year of launch

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