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AOD 9604 is a synthetic peptide fragment derived from the C-terminus of human growth hormone (hGH), specifically amino acids 176191

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This interaction both disrupts peptidoglycan assembly in spore-forming bacilli and promotes the aggregation of nisinlipid complexes that create pores in the cytoplasmic membrane, leading to loss of membrane integrity and cell death (198, 199)

Berberine promotes M2 macrophage polarisation through the IL-4-STAT6 signalling pathway in ulcerative colitis treatment