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In addition, TGR5 may regulate energy homeostasis through activating deiodinases to convert the prohormone thyroxine (T4) into the active hormone triiodothyronine (T3) (164, 165)

Report any: Serious adverse events to your prescriber To the compounding pharmacy that supplied the product Consider submitting a report to the FDA Keep the product packaging, lot numbers, and any unused medication

Activation of these receptors may modulate dopamine signaling, potentially reducing alcohol's rewarding properties, though the exact mechanisms in humans remain under investigation

doi: 10.1111/imr.12886 54 HeimM

[PMID: PMC8294388]