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Neuroprotection of UA may be mediated by the Akt/GSK3 signaling pathway [136]

CoQ10 may indirectly help reduce oxidative stress by reducing inflammation (51)

NAD+ deficiency could indicate muscle loss, oxidative stress, and the start of many life-limiting diseases

64 Similarly, the phosphorylation of 1,4,5-inositoltrisphosphate receptor-associated cGMP kinase substrate, a protein located in the membrane of the endoplasmic reticulum, in a ternary complex initiates the inhibition of the IP 3 -induced release of Ca 2+ from the endoplasmic reticulum, which promotes the relaxation of VSMCs

Gao MG, Liu XH, Du MX, Gu H, Xu H, Zhong XM