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The overexpression of HIF-1, a master regulator involved in cellular adaptation to hypoxia, has been detected in both primary and metastatic colorectal cancer lesions 44

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Macrophage Polarization Your immune system contains macrophages that can either promote inflammation (M1 type) or support tissue repair (M2 type)

Supplementary Tables 12 and 13 and Supplementary Tables 2024 show the top GSEA gene sets for the up- and downregulated genes in siGSTO1 and drug treatment Bru-Seq data sets