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Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus

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1113 Nearly all trials are conducted over shorter durations of time and there is no long-term data available on the effect of orally administered glutathione on skin pigmentation

The authors say the research should serve as a "cautionary tale" about possible long-term health effects of these drugs