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Moreover, some patients may interrupt their treatment once symptoms improve, not realising the long-term necessity of ongoing supplementation to prevent recurrence of deficiency symptoms

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This is not an issue with an injection (since IM/IV bypasses the gut), but if a patient is also taking oral supplements, they should separate them from tetracycline dosing

Retrieved June 10, 2025, from Mayo Clinic

Avoid exceeding your recommended dosage on the medication