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However, when bEnd.3 cells were treated with rTGF 1, claudin-5 immunostaining became increasingly cytoplasmic as doses increased, indicating a disruption of tight junctions (Figure 4c)

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By binding to specific receptors on the anterior pituitary gland, sermorelin stimulates the natural release of human growth hormone (HGH), making it a valuable tool in the treatment of growth hormone deficiency