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Additional symptoms include impaired wound and fracture healing, easy bruising, and loose or decaying teeth

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Key learning topics Therapeutic value and safety of paracetamol and aspirin Mechanisms of toxicity in paracetamol and aspirin overdose Signs and symptoms of paracetamol and aspirin overdose Plasma paracetamol/salicylate used to assess overdose severity Plasma paracetamol/salicylate used to monitor overdose treatment Principles of treatment in paracetamol and aspirin overdose Clinical laboratory staff members are often requested to analyse blood or urine samples for the presence of specific drugs