Hypoglycaemia risk When combined with diabetes medications, particularly insulin or sulfonylureas, berberine may potentiate glucose-lowering effects, increasing hypoglycaemia risk
Conversely, patients seeking weight loss without gastric side effects or those with contraindications to GLP-1 (e.g., personal or family history of medullary thyroid carcinoma) may explore Contrave or other options with their provider
It can be found naturally in foods and beverages like coffee, tea, and chocolate, or as an additive in many common items such as energy drinks and caffeinated sodas
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The Charlson Comorbidity Index (CCI, numeric variable) was calculated based on other comorbidities
