Observational studies and some ophthalmology commentaries have been more reassuring overall, suggesting that many patients taking semaglutide do not experience clinically meaningful retinal worsening
Semaglutide Common side effects may include: Nausea Vomiting Diarrhea Abdominal pain Constipation Heartburn Burping More severe side effects that require immediate medical attention: Ongoing upper stomach pain (with or without vomiting) Rash, itching, or swelling of the eyes, face, mouth, tongue, or throat Difficulty breathing or swallowing Decreased urination or swelling of legs, ankles, or feet Vision changes Fainting or dizziness Rapid heartbeat, anxiety, mood changes, or confusion Semaglutide may affect mental health, leading to symptoms such as depression or suicidal thoughts
& Gutman, M., 1993
If you dont have any reason not to take it, such as kidney disease, creatine may be a good option for people with slow COMT variants who want to avoid methylfolate and methylB12 supplements
SAHPRAs early warning in 2024 In November 2024, SAHPRA issued a formal public warning highlighting the proliferation of falsified, compounded and substandard GLP 1 products being sold through informal channels, websites and social media platforms in South Africa
