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F., Larijani, B., Heshmat, R., Fakhrzadeh, H., Radjabipour, B., Toliat, T., & Raza, M

Research examining human cardiac samples has revealed several key findings: GLP-1R mRNA transcripts have been consistently detected in all four cardiac chambers from human hearts, at levels approximating those in human pancreas [1] Receptor expression is notably absent in cardiac fibroblasts, coronary artery endothelial cells, and vascular smooth muscle cells according to some studies [1] Human GLP-1R expression appears predominantly in cardiomyocytes, albeit at relatively low levels [2] Interestingly, species differences exist in GLP-1R distribution patterns

10.1210/er.2007-0036

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NAD : Nicotinamide adenine dinucleotide (NAD) is an important coenzyme that naturally decreases with age