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ALA's main role in the skin appears to be modulating the immune response of the epidermis

Mammalian autophagy: core molecular machinery and signaling regulation

doi: 10.3390/ijms20102454 101 GaoFLiMLiuWBZhouZSZhangRLiJLet al

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These findings suggest a powerful capacity for dermal thickening and structural improvement, which is highly relevant for softening the appearance of acne scars