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Those diagnosed with malabsorption problems like leaky gut syndrome, celiac disease, and Crohn's disease often require elevated nutrient levels in order to receive the vitamins and minerals they need to stay healthy

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PMID: 18454811.

One study, which also evaluated cognitive function in patients with high MMA concentrations, found no significant effects on the MDD inventory score, but only 30 of the 140 subjects had depression at baseline, which may have diluted any benefits

More serousB12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serous symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia, and changes in reflexes