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Using a mixture of ketone salts and medium-chain triglycerides (KSMCT) as the ketogenic supplement (2.5 g/kg/day), they demonstrated that administration of A 1 R antagonist abolished the anti-seizure effect (i.e., decrease in number of spike-wave discharges SWD) established by 7 days of KSMCT treatment (107) and dose-dependently decreased or abolished the anxiolytic effects of KSMCT treatment (108)